found that in Japanese adults, there is a highly significant inverse correlation between age and Zn concentration in hair ( Yasuda and Tsutsui, 2016 ; Matsuyama et al., 2021 ), and with age covered as one of the variables in multiple regression analysis, a significant negative correlation in levodopa dosing frequency was found ( Yasuda and Tsutsui, 2016 ).
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Serum zinc deficiency is a potential risk factor for the occurrence of levodopa-induced dyskinesia in drug-naïve Parkinson's disease.
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