Abnormal brain structure in atopic dermatitis: Evidence from Mendelian randomization study.

3.1 AD and cortical thickness We found a borderline significant association between AD and the decreased CT in the posterior cingulate (IVW‐MR: β = −0.065, p = 0.018, p‐corrected = 0.551) and isthmus cingulate regions (IVW‐MR: β = −0.086, p = 0.003, p‐corrected = 0.188) (Figure 2 , Table S3 ). 3.2 AD and CA We found a borderline significant association between AD and the decreased SA in the supramarginal region (IVW‐MR: β = −0.047, p = 0.044, p ‐corrected = 0.714) and the increased SA in the isthmus cingulate regions (IVW‐MR: β = 0.053, p = 0.018, p ‐corrected = 0.714) (Figure 2 , Table S3 ).

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The p‐corrected value > 0.05, but the p ‐value < 0.05 was considered a borderline significance. 3 RESULT A total of 20 SNPs were identified as candidate IVs for AD.

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