The results showed a highly significant increase in the mean widening length of the intercellular space on using 25% span 60 as a granulating agent, compared to using either pure drug, 15% span 60, or 20% span 60 as a granulating agent at ( p < 0.001) (Table 5 and Fig. 11 ).
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An industrial procedure for the intestinal permeability enhancement of acyclovir: in-vitro and histological evidence.
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