Cell-type-specific optogenetic stimulation of the locus coeruleus induces slow-onset potentiation and enhances everyday memory in rats.

Proc Natl Acad Sci U S A · 2023 · PMC10655220 · PMID 37931094

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a nonsignificant trendP = 0.06so close (0.05 < p ≤ 0.1)

Comparisons with baseline (100%, one-sample t tests with Bonferroni correction for multiple comparisons) revealed no significant potentiation in the SCH 23390-treated group (t 4 = 1.08, P = 0.68) but a nonsignificant trend toward potentiation in the propranolol group 120 to 180 min after light stimulation (t 4 = 3.29, P = 0.06; Fig. 3 E , right panel).

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