Medial Temporal Lobe Atrophy in Predementia Alzheimer's Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort.

J Alzheimers Dis · 2023 · PMC10657682 · PMID 37248900

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0560

boldest claim

The sentences

highly significantp < 0.001actually significant

ERC and posterior hippocampus were the only subregions with highly significant ( p < 0.001) lower baseline volumes in both MCI A+ compared to NC A–, and in A+/T+orN+ compared to A–/T–/N–.

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borderline significantp = 0.056so close (0.05 < p ≤ 0.1)

In amyloid positive MCI compared to amyloid negative controls, there were significantly smaller volumes in ERC, anterior and posterior hippocampus (all p < 0.01), while BA35 were borderline significant smaller ( p = 0.056).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.