A network was produced by the highest scoring network with a total of 32 DEGs and a highly significant score of 77 (ATP 5F1D, ATP5 MG, ECSIT, GRPEL1, HPF1, Mitochondrial complex 1, MRPL11, MRPL40, NRPL44, MRPS18C, MRPS23, MRPS24, MRPS25, MRPS28, MRPS7, MRPF, NADH-dehydrogenase, NDUFA6, NDUFA68, NDUFA6, NDUFA10, NDUFB5, NDUFB7, NDUFS6, NFkB (complex), RTF1, TIMM21, TIMMDC1, TMEM223, TEME70, TRMT10C, UBXN1) ( Fig. 4 ).
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Mediating a host cell signaling pathway linked to overwinter mortality offers a promising therapeutic approach for improving bee health.
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