Dysregulated noradrenergic response is associated with symptom severity in individuals with schizophrenia.

There was a significant main effect of trial condition ( F (1, 49) = 9.90, p = 0.003, η (2)= 0.16), trial-by-group interaction ( F (1, 49) = 8.16, p = 0.006, η (2)= 0.14) and a trend towards significance for group ( F (1, 49) = 3.27, p = 0.07, η (2)= 0.06).

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We found a trend toward significance for individuals with schizophrenia to make more errors than controls (healthy subjects: mean = 0.30, SD = 0.20; individuals with schizophrenia: mean = 0.38, SD = 0.13; t = 1.78, p = 0.08).

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