For example, NS-components of β -cells might be indicative of β -cells coupled via gap junction linkages that may play a functional role in coordinated responses to endogenous insulin secretagogues such as glucagon-like peptide-1 (GLP-1), but might not be significant for islet dynamics involved in glucose-stimulated Ca 2+ oscillations [ 64 , 65 ].
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Geometric and topological characterization of the cytoarchitecture of islets of Langerhans.
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