Evaluating the performance of low-frequency variant calling tools for the detection of variants from short-read deep sequencing data.

Sci Rep · 2023 · PMC10665316 · PMID 37993475

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Specifically, SiNVICT and outLyzer showed an increasing trend in the F1-score when the sequencing depth was less than 5000X, while Pisces and LoFreq exhibited a decreasing trend.

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