The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence

Biomedicines · 2023 · PMC10669206

Europe PMC

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an increasing trendno p-value reported

However, these findings differed in HaCaT keratinocytes, where only NB-UVB led to robustly increased mRNA expression of senescence markers, whereas BB-UVB resulted in an increasing trend of senescence markers’ mRNA expression.

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a decreasing trendno p-value reported

The expression of RNU1 , miR-125 and miR-138 showed a decreasing trend following UVB treatments as compared with the control ( Figure 7 B,D,E).

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