Heteroplasmy and Individual Mitogene Pools: Characteristics and Potential Roles in Ecological Studies.

Biology (Basel) · 2023 · PMC10669347 · PMID 37998051

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may not be significantno p-value reported

However, it is rational to expect that the effects of heteroplasmic variants in tissues are dose-dependent and that the functional reduction in the entire OXPHOS system may not be significant, provided that the proportion of deleterious variants does not exceed a certain threshold [ 48 ].

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