IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling.

Commun Biol · 2023 · PMC10673909 · PMID 38001239

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

trending toward significanceP = 0.053so close (0.05 < p ≤ 0.1)

In the LV, the percentages of CD3 + CD4 − cardiac fibroblasts were higher in the SuHx conditions and trending toward significance compared to Nx conditions (2.10% ± 0.71% vs 9.41% ± 6.04%, P = 0.053).

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highly significantno p-value reported

Functional gene ontology (GO) enrichment analysis of the conditional media secreted proteins using the g:profiler web server showed humoral immune response, immune effector process, leukocyte-mediated immunity, vesicle-mediated transport, platelet degranulation, neutrophil activation and lymphocyte-mediated immunity as highly significant for a search of biological processes (BP) (Fig. 5e ) similar to the gene expression data.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.