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Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors.

Strahlenther Onkol · 2023 · PMC10674014 · PMID 37420037

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a decreasing trendno p-value reported
Moreover, the addition of AZD6738 enhanced infiltration; increased cell proliferation and the ability to produce IFN‐γ from CD8+ T cells derived from TILs; and caused a decreasing trend in the number of TILs and Tregs, and depleted T cells in mouse xenografts.

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