The pharmacokinetic benefits of these temperature-sensitive hydrogels for NSAID loading and delivery may be significant because a depot formulation can be generated and an anti-inflammatory drug (MX in our study) can be gradually eluted, preserving a constant local concentration of a drug in the surrounding tissues for a long period of time.
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Thermosensitive Polyurethane-Based Hydrogels as Potential Vehicles for Meloxicam Delivery.
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