Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIV_mac239 in rhesus macaques.

41 Despite lower viral loads and innate gene expression, lack of vpr was (on average) associated with enrichment of NF-κB target gene expression at later time points (8, 12, and 24 wpi), although the differences to the wt group failed to reach significance ( Figure 2 A).

also in 4,113 other papers