The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50+ is mediated by age and biomarkers of cardiovascular disease.

Cardiovasc Res · 2023 · PMC10683948 · PMID 37052588

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borderline significantno p-value reported

In univariable regression analysis with scaled WMH as a dependant variable, cystatin C at Wave 1 (OR per 1 unit increase = 3.32 (95% CI, 1.11 to 9.98), and CKD-EPI eGFRcys at Wave 1 (OR per 1 unit increase = 0.98 (95% CI, 0.97 to 0.99) were significant predictors, whereas CKD-EPI eGFRcre at Wave 1 was borderline significant [OR per 1 unit increase = 0.99 (95% CI, 0.97 to 1.00)].

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