Branched chain amino acids harbor distinct and often opposing effects on health and disease.

Commun Med (Lond) · 2023 · PMC10684599 · PMID 38017291

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highly significantno p-value reported

For example, a recent meta-analysis reported very precise and highly significant relative risks for one standard deviation increases in isoleucine, leucine, and valine with type 2 diabetes of 1.54 (95% confidence interval [CI]: 1.36, 1.74), 1.40 (95% CI: 1.29, 1.52), and 1.40 (95% CI: 1.25, 1.57), respectively 21 .

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