Consistent with the GO analysis, the differences in the expression of multiple genes in the ECM network, including collagens ( COL1A1, COL1A2, COL3A1, COL4A1 ), fibronectin ( FN1 ), Lumican ( LUM ) and Osteonectin ( SPARC ), are highly significant in vivo compared to in vitro.
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Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment.
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