Barely Significant
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A Potential Pitfall and Clinical Solutions in Surface-Guided Deep Inspiration Breath Hold Radiation Therapy for Left-Sided Breast Cancer.

Adv Radiat Oncol · 2023 · PMC10692299 · PMID 38047221

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may not be significantno p-value reported
Although the <1 Gy reduction of D Mean is also statistically significant, clinically it may not be significant as the risk of long-term heart ischemic event is reduced by only <20% with a D Mean reduction of <1 Gy. 1 For tangent plans, the heart ∆D Mean = –1.4 ± 1.4 Gy is already low at DIBH ( Table 3 ) by using the MLC heart blocking.

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