Aerobic exercise combined with chlorogenic acid exerts neuroprotective effects and reverses cognitive decline in Alzheimer's disease model mice (APP/PS1) via the SIRT1/ /PGC-1α/PPARγ signaling pathway.

Front Aging Neurosci · 2023 · PMC10693339 · PMID 38046466

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a decreasing trendno p-value reported

Interestingly, with regard to IL-6 expression, there was no significant difference between the three treatment modalities, although all three groups of AD mice receiving treatment showed a decreasing trend.

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