Nano-modulators with the function of disrupting mitochondrial Ca²⁺ homeostasis and photothermal conversion for synergistic breast cancer therapy.

When the concentration of Cur varied from 5.6 to 22.4 μg/mL, the cytotoxicity of Cur, SCCI and SCCL + L groups were extremely significant differences, indicating that the synergistic effect of chemotherapy, photothermal therapy and mitochondrial Ca 2+ overload could effectively kill 4T1 cells.

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