<i>In vitro</i> Evaluation of Cytotoxic Effects of Methanolic Leaf Extracts of <i>Annona muricata</i> on Oral Squamous Cell Carcinoma-15 Cell Lines and its Effect On Expression of Bcl 2-associated X protein, B-cell C/Lymphoma 2 and p53 Genes.

Contemp Clin Dent · 2023 · PMC10699191 · PMID 38075540

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A highly significant decrease was observed in Bcl-2 gene expression ( P < 0.05), whereas p53 and BAX genes revealed a highly significant increase ( P < 0.05) when SCC-15 cell lines were treated with LEAM in the study group compared to the control.

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