ANOVA and posthoc means comparisons demonstrated a clear stepwise concentration–response; the 2-fold induction of cyp1a mRNA in the 0.25 g/kg exposure was marginally significant ( p = 0.07), while the 3.7-fold and 29-fold induction in the 0.5 g/kg ( P = 0.002) and 1.0 g/kg ( P < 0.001) exposures were highly significant.
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Biological Responses of Pacific Herring Embryos to Crude Oil Are Quantifiable at Exposure Levels Below Conventional Limits of Quantitation for PAHs in Water and Tissues.
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