The realistic positioning of UVA1 phototherapy after 25 years of clinical experience and the availability of new biologics and small molecules: a retrospective clinical study.

However, we have noted a decreasing trend in the number of patients who started a first cycle of therapy ( Figure 2 and Table 1 ): after the first years (1998–2001) in which we familiarized with the new technique, the number of patients per year was quite stable ranging from 36 to 39 in the years 2002 to 2013 but, afterwards it started to decline to 18–20 since 2018 to 2022.

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