Barely Significant
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Scientific opinion on the tolerable upper intake level for manganese.

EFSA J · 2023 · PMC10704406 · PMID 38075631

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may be significantno p-value reported
Data suggest that the lysosomes, the Golgi apparatus, the endosome, mitochondria as well as the nucleus may be significant pools of intracellular manganese and targets of its toxicity with most studies focusing on mitochondrial dysfuntion (Chen et al., 2018 ). 3.4.3.1.

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