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<i>Echinacea purpurea</i> (L.) Moench Polysaccharide Alleviates DSS-Induced Colitis in Rats by Restoring Th17/Treg Balance and Regulating Intestinal Flora.

Foods · 2023 · PMC10706068 · PMID 38231750

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a decreasing trendno p-value reported
EPP Restores the Th17/Treg Balance in Colitic Rats The proportion of Th17 cells in DSS-treated rat spleen cells significantly increased (from 1.87% to 2.54%), while Treg cells showed a decreasing trend but no significant difference.

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an increasing trendno p-value reported
The experimental results showed an increasing trend in the gene expression of IL-23 that tended to increase in the M group, while the gene expression of IL-17A secreted by Th17 cells was significantly higher, and EPP could effectively inhibit this trend.

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