Slow myosin heavy chain 1 is required for slow myofibril and muscle fibre growth but not for myofibril initiation.

Although smyhc1 stl583 homozygotes lack of F59 immunoreactivity, it may be significant that the F59 epitope is in an unmapped region of the myosin S1 head ( Crow and Stockdale, 1986 ) and could therefore be absent in a truncated protein.

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