Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling.

47 The most recent GWAS for JT and QT intervals found highly significant associations, respectively, with rs17171731 ( P = 4E-23) and rs1335516 ( P = 1E-43, in very high LD with each other in European ancestry populations), with the AF risk allele associated with longer durations. 48 The GTEx project shows relatively low expression of FAM13B in human left ventricle (median value 5.5 transcripts per million), and no significant left ventricle FAM13B eQTLs are detected.

also in 23,678 other papers