Alanine aminotransferase to high- density lipoprotein cholesterol ratio is positively correlated with the occurrence of diabetes in the Chinese population: a population-based cohort study.

Figure 2 displays the Kaplan-Meier curves of cumulative incidence of diabetes according to quintiles of the ALT/HDL-C ratio, showing an increasing trend in cumulative incidence of diabetes with increasing quintiles of the ALT/HDL-C ratio (log-rank P < 0.001).

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In addition, we found that except for HDL-C, which showed a decreasing trend, other indicators such as height, weight, BMI, SBP, DBP, FPG, TC, TG, LDL-C, ALT, AST, BUN, and Cr levels increased with increasing quintiles of the ALT/HDL-C ratio.

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Four multivariable-adjusted models were established, and a positive trend was observed between the ALT/HDL-C ratio as a continuous variable and the risk of incident diabetes in the crude model and Models 1-3.

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