Activation of GPER1 in macrophages ameliorates UUO-induced renal fibrosis.

Cell Death Dis · 2023 · PMC10716282 · PMID 38086848

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an increasing trendno p-value reported

4C ), as demonstrated by increased Nlrp3 and Ccl7 mRNA levels and an increasing trend in Lcn2 and Il1b mRNA (Supplementary Fig. 4D ).

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a decreasing trendno p-value reported

A decreasing trend of Nlrp3 and Lcn2 mRNA was also observed (Fig. 9I ), indicating that GPER1 activation in macrophages could protect co-cultured TECs from injuries.

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