When the APC and the lower boundary of the 95% CI were both positive, this was considered an increasing trend.
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Global Epidemiology of Cirrhosis: Changing Etiological Basis and Comparable Burden of Nonalcoholic Steatohepatitis between Males and Females.
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The sentences
When the APC and the upper boundary of the 95% CI were both negative, this was considered a decreasing trend.