Magnitude and time course of insulin resistance accumulation with the risk of cardiovascular disease: an 11-years cohort study.

Cardiovasc Diabetol · 2023 · PMC10720129 · PMID 38093281

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a decreasing trendno p-value reported

Additionally, incorporation of both cumMETS-IR and the time course, the results showed that same cumMETS-IR exposure accumulated with an increasing trend compared with a decreasing trend contributed more to the subsequent risk of CVD.

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an increasing trendno p-value reported

Conclusions The risk of CVD increased with elevated cumMETS-IR and an increasing trend over time, emphasizing the importance of maintaining optimal METS-IR levels across life span.

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