Barely Significant
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Global, regional, and national burden of gallbladder and biliary diseases from 1990 to 2019.

World J Gastrointest Surg · 2023 · PMC10725539 · PMID 38111771

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an increasing trendno p-value reported
SDI regions levels From 1990 to 2019, the number of incident cases showed an increasing trend in both sexes, and since 2018, it began to decrease in the high- and middle-SDI quintiles.

also in 63,971 other papers

a decreasing trendno p-value reported
The ASYR in females and males showed a decreasing trend in the high-SDI and high-middle-SDI regions.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.