Analysis based on age-defined groups revealed that ECOG performance and anemia were highly significant in the older cohort, whereas B symptoms emerged as the most significant parameter in the younger cohort.
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Integrative analysis of clinicopathological features defines novel prognostic models for mantle cell lymphoma in the immunochemotherapy era: a report from The North American Mantle Cell Lymphoma Consortium.
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This initiative was aimed at fulfilling the need for new therapy development, as there is an increasing trend of investigations conducted specifically in younger or older patient populations.