Quality of life and associated factors of heroin-dependent patients receiving methadone and buprenorphine maintenance treatment.

Starting in 2009, there was a decreasing trend in the prevalence of heroin use, which might be related to the implementation of the national harm reduction program in 2006. 24 While methadone was introduced in the harm reduction program implemented by the Taiwanese government in 2006, buprenorphine then became available as MOUD in 2009. 25 Buprenorphine was previously prescribed as an analgesic in sublingual or intravenous form.

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