Mitochondrial Dysfunction in Metabolic Dysfunction Fatty Liver Disease (MAFLD).

Int J Mol Sci · 2023 · PMC10743953 · PMID 38139341

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an elevated trendno p-value reported

The transcription of PGC-1 is involved in the mitochondrial antioxidant mechanism, and the accumulation of cytochrome P450 2E1 (CYP2E1) mutations affects ETC reaction activity and stimulates the accumulation of mt-ROS, resulting in an elevated trend in MAFLD [ 51 ].

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