Pharmacokinetics and Safety of Group A and B Anti-Tuberculosis Drugs Used in Treatment of Rifampicin-Resistant Tuberculosis during Pregnancy and Post-Partum: A Narrative Review.

Pathogens · 2023 · PMC10745846 · PMID 38133270

Europe PMC DOI

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may not be significantno p-value reported

The drug is highly lipophilic and highly protein-bound, with a huge volume of distribution, which may or may not be significant in pregnancy as plasma protein concentrations are decreased while fat stores are increased [ 10 ].

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