Barely Significant
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Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants.

J Virol · 2023 · PMC10746274 · PMID 38019013

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an overall trendno p-value reported
While each type of binding footprint presented an overall trend in affinity for the B.1.351 VOC, it is worth noting that select constructs from each binding footprint type retained binding affinity and neutralization activity against VOCs.

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