Agonistic Bivalent Human scFvs-Fcγ Fusion Antibodies to OX40 Ectodomain Enhance T Cell Activities against Cancer.

C41Fc significantly increased the percentage of granzyme B-producing cells in the CD3 + and CD4 + T cell populations ( Figure 8 D and Figure 8 H, respectively), but only showed an increasing trend for intracellular cytokines in all three T cell populations, and for granzyme B only in the CD8 + population ( p > 0.05).

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