Epidemiology of <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> bloodstream infections in a general hospital in Singapore: a retrospective cohort study.

pneumoniae BSI cases show an increasing trend worldwide, with resistance to certain key antimicrobials such as ciprofloxacin, third-generation cephalosporins and carbapenems rising to alarming levels.[ 2 - 4 ] This is of great concern owing to the burden it places on patient safety, healthcare systems and the economy.

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