The results indicated that compared to that of control rats, tau phosphorylation level in the hippocampus of the STP rats was increased at Ser199 (pS199), Thr231 (pT231), Ser262 (pS262), and AT8 (Ser202, Thr205), but not at Ser396 (pS396) and Ser404 (pS404) site (with only an increasing trend).
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Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer's disease-like neuropathology and cognitive deficits.
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