Between 1990 and 2019, there has been an increasing trend in the development of IE, with one study finding an increase from 6.2/100,000 person-years to 10.2/100,000 person-years [ 12 , 16 , 17 , 25 , 33 ].
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Between 1990 and 2019, there has been an increasing trend in the development of IE, with one study finding an increase from 6.2/100,000 person-years to 10.2/100,000 person-years [ 12 , 16 , 17 , 25 , 33 ].