Islet transplantation outcomes in type 1 diabetes and transplantation of HLA-DQ8/DR4: results of a single-centre retrospective cohort in Canada.

EClinicalMedicine · 2024 · PMC10758748 · PMID 38169703

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

of borderline significancep = 0.057so close (0.05 < p ≤ 0.1)

those who received transplants from donors positive for both HLA-DQ2∗-A05 and–DQ8 had inferior outcomes of borderline significance (p = 0.057; Figure S3B ).

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highly significantno p-value reported

The study identified that receiving islets from donors positive for HLA-DQ8 (-DR4) has a highly significant protective effect on islet graft survival.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.