Naringenin modulates GABA mediated response in a sexdependent manner in substantia gelatinosa neurons of trigeminal subnucleus caudalis in immature mice.

In contrast, for fast GABA responses, the relative amplitudes demonstrated a decreasing trend with increasing naringenin concentration, naringenin 1 μM: 1.00 ± 0.088; 10 μM: 0.96 ± 0.244; 100 μM: 0.74 ± 0.221; 1 mM: 0.23 ± 0.086 ( Fig. 4D , n = 5, p < 0.01; one-way ANOVA).

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