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Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes.

Arthritis Res Ther · 2024 · PMC10763221 · PMID 38173036

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an expected trendno p-value reported
This was an expected trend, as excessive matrix breakdown via decreased matrix synthesis and increased MMP and aggrecanase activity is a hallmark of cartilage disease [ 54 , 55 ].

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