Barely Significant
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Characterization of the RofA regulon in the pandemic M1<sub>global</sub> and emergent M1<sub>UK</sub> lineages of <i>Streptococcus pyogenes</i>.

Microb Genom · 2023 · PMC10763501 · PMID 38117674

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an apparent trendno p-value reported
There was an apparent trend for mice infected with S. pyogenes carrying the rofA three SNPs (GAS-M1 H1488rofA3SNPs ) to cause more intense infection lasting up to 7 days (Fig.

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may be significantno p-value reported
Reversal of the RofA three SNPs in M1 UK As the RofA regulon in M1 UK appeared distinct from M1 global , it seemed possible that the three SNPs present in rofA in the M1 UK lineage may be significant in this strain background, noting that the strain background is characterized by a number of additional SNPs that may alter strain physiology.

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