Canagliflozin was also borderline significant when compared with empagliflozin [RR 0.90 (0.82–0.99)] and sotagliflozin [RR 0.85 (0.73–1.00)] (see Supplementary Table S4 ) Supplementary Figure S5C and Supplementary Table S3 show the probability of serious AEs of each SGLT2i.
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Comparative cardiovascular benefits of individual SGLT2 inhibitors in type 2 diabetes and heart failure: a systematic review and network meta-analysis of randomized controlled trials.
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