on the threshold of significanceP -value < 5.0 × 10 -8
Each predictive model included a PRS, along with age and sex, and was poorly predictive of BCC risk in the Hispanic/Latino sample from the GERA cohort with an area under the curve (AUC) value of 0.545 and 0.573, depending on the threshold of significance for the SNPs ( P -value < 5.0 × 10 -8 and P < 1.0 × 10 -6 , respectively) (Supplementary Fig. 8 ).