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Predicting the onset of preeclampsia by longitudinal monitoring of metabolic changes throughout pregnancy with Raman spectroscopy.

Bioeng Transl Med · 2024 · PMC10771567 · PMID 38193120

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an increasing trendno p-value reported
38 , 39 Cholesterol (Figure 3b ) generally shows an increasing trend in all three trimesters but most significant early in pregnancy.

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a decreasing trendno p-value reported
58 We observe that citric/succinic acid, intermediate metabolites in the TCA cycle, (940 cm −1 , Figure 3o ) has a decreasing trend through pregnancy, but in each trimester it is amplified in the preeclamptic cohort.

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