38 , 39 Cholesterol (Figure 3b ) generally shows an increasing trend in all three trimesters but most significant early in pregnancy.
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Predicting the onset of preeclampsia by longitudinal monitoring of metabolic changes throughout pregnancy with Raman spectroscopy.
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58 We observe that citric/succinic acid, intermediate metabolites in the TCA cycle, (940 cm −1 , Figure 3o ) has a decreasing trend through pregnancy, but in each trimester it is amplified in the preeclamptic cohort.