<i>CYP1B1</i> promotes colorectal cancer liver metastasis by enhancing the growth of metastatic cancer cells via a fatty acids-dependent manner.

J Gastrointest Oncol · 2023 · PMC10772677 · PMID 38196537

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As “CYP1B1-LCFAs-G1/S transition” may be significant mechanisms for progression of CRC LM, perturbing fatty acid synthesis opens a new revenue for treatment of LM, especially targeting “CYP1B1-LCFAs”, which will become a new method ( Figure 7 ).

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